Overrepresentation of transcription factor families in the genesets underlying breast cancer subtypes

BACKGROUND: The human genome contains a large amount of cis-regulatory DNA elements responsible for directing both spatial and temporal gene-expression patterns. Previous studies have shown that based on their mRNA expression breast tumors could be divided into five subgroups (Luminal A, Luminal B,...

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Bibliographic Details
Main Authors: Joshi, Himanshu, Nord, Silje H, Frigessi, Arnoldo, Børresen-Dale, Anne-Lise, Kristensen, Vessela N
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3441847/
https://ncbi.nlm.nih.gov/pubmed/22616941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-13-199
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