Clonal Hematopoiesis and Premalignant Diseases

Clonal hematopoiesis (CH) arises when mutations in the hematopoietic system confer a fitness advantage to specific clones, thereby favoring their disproportionate growth. The presence of CH increases with age and environmental exposures such as cytotoxic chemotherapy or radiotherapy. The most freque...

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Bibliographic Details
Published in:Cold Spring Harb Perspect Med
Main Authors: Kaner, Justin, Desai, Pinkal, Mencia-Trinchant, Nuria, Guzman, Monica L., Roboz, Gail J., Hassane, Duane C.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2020
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Perspectives
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117948/
https://ncbi.nlm.nih.gov/pubmed/31615870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a035675
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