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Engineering the AAV Capsid to Evade Immune Responses

Gene therapy is progressively emerging as a promising and powerful therapeutic modality, and adeno-associated virus (AAV) is a major delivery vehicle for such therapies. Among the most significant challenges that limit AAV’s utility, however, is the immune response it elicits. Antibodies elicited by...

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Detalhes bibliográficos
Publicado no:Curr Opin Biotechnol
Main Authors: Barnes, Christopher, Scheideler, Olivia, Schaffer, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7117822/
https://ncbi.nlm.nih.gov/pubmed/30807882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2019.01.002
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