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Discovery of Keap1−Nrf2 small−molecule inhibitors from phytochemicals based on molecular docking

Various phytochemicals have been reported to protect against oxidative stress. However, the mechanism underlying has not been systematically evaluated, which limited their application in disease treatment. Nuclear factor erythroid 2−related factor 2 (Nrf2), a central transcription factor in oxidativ...

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Библиографические подробности
Опубликовано в: :Food Chem Toxicol
Главные авторы: Li, Maiquan, Huang, Weisu, Jie, Fan, Wang, Mengmeng, Zhong, Yongheng, Chen, Qi, Lu, Baiyi
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier Ltd. 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116978/
https://ncbi.nlm.nih.gov/pubmed/31412289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2019.110758
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