The emergence of the brain non-CpG methylation system in vertebrates

Mammalian brains feature exceptionally high levels of non-CpG DNA methylation alongside the canonical form of CpG methylation. Non-CpG methylation plays a critical regulatory role in cognitive function, which is mediated by the binding of MeCP2, the transcriptional regulator that when mutated causes...

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Détails bibliographiques
Publié dans:Nat Ecol Evol
Auteurs principaux: de Mendoza, Alex, Poppe, Daniel, Buckberry, Sam, Pflueger, Jahnvi, Albertin, Caroline B., Daish, Tasman, Bertrand, Stephanie, de la Calle-Mustienes, Elisa, Gomez-Skarmeta, Jose Luis, Nery, Joseph R., Ecker, Joseph R., Baer, Boris, Ragsdale, Clifton W., Grützner, Frank, Escriva, Hector, Venkatesh, Byrappa, Bogdanovic, Ozren, Lister, Ryan
Format: Artigo
Langue:Inglês
Publié: 2021
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116863/
https://ncbi.nlm.nih.gov/pubmed/33462491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41559-020-01371-2
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