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A general carbonyl alkylative amination for tertiary amine synthesis facilitated by visible light

The ubiquity of tertiary alkylamines in pharmaceutical and agrochemical agents, natural products and smallmolecule biological probes(1,2) continues to stimulate enormous efforts towards their streamlined synthesis(3–9). Arguably, the most robust method for tertiary alkylamine synthesis is carbonyl r...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Kumar, Roopender, Flodén, Nils J., Whitehurst, William G., Gaunt, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116815/
https://ncbi.nlm.nih.gov/pubmed/32268340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2213-0
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