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Copper-Catalyzed Alkylation of Aliphatic Amines Induced by Visible Light

Although the alkylation of an amine by an alkyl halide serves as a “textbook example” of a nucleophilic substitution reaction, the selective mono-alkylation of aliphatic amines by unactivated, hindered halides persists as a largely unsolved challenge in organic synthesis. We report herein that prima...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Matier, Carson D., Schwaben, Jonas, Peters, Jonas C., Fu, Gregory C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6044445/
https://ncbi.nlm.nih.gov/pubmed/29182328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b09582
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