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The Design of a Photoredox Catalyst that Enables the Direct Synthesis of Carbamate-Protected Primary Amines via Photoinduced, Copper-Catalyzed N-Alkylation Reactions of Unactivated Secondary Halides

Despite the long history of S(N)2 reactions between nitrogen nucleophiles and alkyl electrophiles, many such substitution reactions remain out of reach. In recent years, efforts to develop transition-metal catalysts to address this deficiency have begun to emerge. In this report, we address the chal...

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Bibliografiske detaljer
Udgivet i:J Am Chem Soc
Main Authors: Ahn, Jun Myun, Peters, Jonas C., Fu, Gregory C.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039098/
https://ncbi.nlm.nih.gov/pubmed/29200268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b10907
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