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The Design of a Photoredox Catalyst that Enables the Direct Synthesis of Carbamate-Protected Primary Amines via Photoinduced, Copper-Catalyzed N-Alkylation Reactions of Unactivated Secondary Halides

Despite the long history of S(N)2 reactions between nitrogen nucleophiles and alkyl electrophiles, many such substitution reactions remain out of reach. In recent years, efforts to develop transition-metal catalysts to address this deficiency have begun to emerge. In this report, we address the chal...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Ahn, Jun Myun, Peters, Jonas C., Fu, Gregory C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6039098/
https://ncbi.nlm.nih.gov/pubmed/29200268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b10907
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