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Copper-Catalyzed Alkylation of Aliphatic Amines Induced by Visible Light
Although the alkylation of an amine by an alkyl halide serves as a “textbook example” of a nucleophilic substitution reaction, the selective mono-alkylation of aliphatic amines by unactivated, hindered halides persists as a largely unsolved challenge in organic synthesis. We report herein that prima...
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| Veröffentlicht in: | J Am Chem Soc |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6044445/ https://ncbi.nlm.nih.gov/pubmed/29182328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b09582 |
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