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Visible-light mediated carbonyl trifluoromethylative amination as a practical method for the synthesis of β-trifluoromethyl tertiary alkylamines

We report the development of an operationally straigtforward, visible-light-mediated multicomponent strategy for the construction of β-trifluoromethylated tertiary alkylamines from feedstock aldehydes, secondary amines and a convenient source of trifluoromethyl iodide. The new process does not requi...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Kolahdouzan, Kavoos, Kumar, Roopender, Gaunt, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society of Chemistry 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8162877/
https://ncbi.nlm.nih.gov/pubmed/34094424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc04853d
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