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Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression
NUP98 fusion proteins cause leukemia via unknown molecular mechanisms. All NUP98 fusion proteins share an intrinsically disordered region (IDR) in the NUP98 N terminus, featuring repeats of phenylalanine-glycine (FG), and C-terminal fusion partners often function in gene control. We investigated whe...
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| Publicat a: | Nat Struct Mol Biol |
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| Autors principals: | , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116736/ https://ncbi.nlm.nih.gov/pubmed/33479542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-00550-w |
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