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Reconstitution of Translesion Synthesis Reveals a Mechanism of Eukaryotic DNA Replication Restart
Leading-strand template aberrations cause helicase-polymerase uncoupling and impede replication fork progression, the details of how uncoupled forks are restarted are uncertain. Using purified proteins from Saccharomyces cerevisiae, we have reconstituted translesion synthesis (TLS) mediated restart...
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| 出版年: | Nat Struct Mol Biol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116498/ https://ncbi.nlm.nih.gov/pubmed/32341533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0418-4 |
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