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Reconstitution of Translesion Synthesis Reveals a Mechanism of Eukaryotic DNA Replication Restart
Leading-strand template aberrations cause helicase-polymerase uncoupling and impede replication fork progression, the details of how uncoupled forks are restarted are uncertain. Using purified proteins from Saccharomyces cerevisiae, we have reconstituted translesion synthesis (TLS) mediated restart...
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116498/ https://ncbi.nlm.nih.gov/pubmed/32341533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0418-4 |
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