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Translesion DNA Synthesis and Mutagenesis in Eukaryotes

The structural features that enable replicative DNA polymerases to synthesize DNA rapidly and accurately also limit their ability to copy damaged DNA. Direct replication of DNA damage is termed translesion synthesis (TLS), a mechanism conserved from bacteria to mammals and executed by an array of sp...

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Detalhes bibliográficos
Autor principal: Sale, Julian E.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3578355/
https://ncbi.nlm.nih.gov/pubmed/23457261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012708
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