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Translesion DNA Synthesis and Mutagenesis in Eukaryotes
The structural features that enable replicative DNA polymerases to synthesize DNA rapidly and accurately also limit their ability to copy damaged DNA. Direct replication of DNA damage is termed translesion synthesis (TLS), a mechanism conserved from bacteria to mammals and executed by an array of sp...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2013
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3578355/ https://ncbi.nlm.nih.gov/pubmed/23457261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a012708 |
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