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CDK11 is required for transcription of replication-dependent histone genes
Replication-dependent histones (RDH) are required for packaging of newly synthetized DNA into nucleosomes during S-phase when their expression is highly upregulated. However, the mechanisms of this upregulation in metazoan cells remain poorly understood. Using iCLIP and ChIP-seq, we found that human...
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| 發表在: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2020
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7116321/ https://ncbi.nlm.nih.gov/pubmed/32367068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0406-8 |
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