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The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes

Various cyclin-dependent kinase (Cdk) complexes have been implicated in the regulation of transcription. In this study, we identified a 70-kDa Cyclin K (CycK) that binds Cdk12 and Cdk13 to form two different complexes (CycK/Cdk12 or CycK/Cdk13) in human cells. The CycK/Cdk12 complex regulates phosph...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Blazek, Dalibor, Kohoutek, Jiri, Bartholomeeusen, Koen, Johansen, Eric, Hulinkova, Petra, Luo, Zeping, Cimermancic, Peter, Ule, Jernej, Peterlin, B. Matija
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cold Spring Harbor Laboratory Press 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205586/
https://ncbi.nlm.nih.gov/pubmed/22012619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.16962311
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