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The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes
Various cyclin-dependent kinase (Cdk) complexes have been implicated in the regulation of transcription. In this study, we identified a 70-kDa Cyclin K (CycK) that binds Cdk12 and Cdk13 to form two different complexes (CycK/Cdk12 or CycK/Cdk13) in human cells. The CycK/Cdk12 complex regulates phosph...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Cold Spring Harbor Laboratory Press
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3205586/ https://ncbi.nlm.nih.gov/pubmed/22012619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.16962311 |
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