The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes

Various cyclin-dependent kinase (Cdk) complexes have been implicated in the regulation of transcription. In this study, we identified a 70-kDa Cyclin K (CycK) that binds Cdk12 and Cdk13 to form two different complexes (CycK/Cdk12 or CycK/Cdk13) in human cells. The CycK/Cdk12 complex regulates phosph...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Blazek, Dalibor, Kohoutek, Jiri, Bartholomeeusen, Koen, Johansen, Eric, Hulinkova, Petra, Luo, Zeping, Cimermancic, Peter, Ule, Jernej, Peterlin, B. Matija
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2011
Soggetti:
Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3205586/
https://ncbi.nlm.nih.gov/pubmed/22012619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.16962311
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi