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CDK11 is required for transcription of replication-dependent histone genes

Replication-dependent histones (RDH) are required for packaging of newly synthetized DNA into nucleosomes during S-phase when their expression is highly upregulated. However, the mechanisms of this upregulation in metazoan cells remain poorly understood. Using iCLIP and ChIP-seq, we found that human...

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Publicado en:Nat Struct Mol Biol
Autores principales: Gajdušková, Pavla, de Los Mozos, Igor Ruiz, Rájecký, Michal, Hluchý, Milan, Ule, Jernej, Blazek, Dalibor
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7116321/
https://ncbi.nlm.nih.gov/pubmed/32367068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-020-0406-8
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