A truncated fragment of Ov-ASP-1 consisting of the core pathogenesis-related-1 (PR-1) domain maintains adjuvanticity as the full-length protein

The Onchocerca volvulus activation-associated secreted protein-1 (Ov-ASP-1) has good adjuvanticity for a variety of antigens and vaccines, probably due to its ability activate antigen-processing cells (APCs). However, the functional domain of Ov-ASP-1 as an adjuvant is not clearly defined. Based on...

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Detalhes bibliográficos
Publicado no:Vaccine
Main Authors: Guo, Jingjing, Yang, Yi, Xiao, Wenjun, Sun, Weilai, Yu, Hong, Du, Lanying, Lustigman, Sara, Jiang, Shibo, Kou, Zhihua, Zhou, Yusen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Ltd. 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7115538/
https://ncbi.nlm.nih.gov/pubmed/25736195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2015.02.053
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