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The Integrity of α-β-α Sandwich Conformation Is Essential for a Novel Adjuvant TFPR1 to Maintain Its Adjuvanticity

TFPR1 is a novel peptide vaccine adjuvant we recently discovered. To define the structural basis and optimize its application as an adjuvant, we designed three different truncated fragments that have removed dominant B epitopes on TFPR1, and evaluated their capacity to activate bone marrow-derived d...

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Dades bibliogràfiques
Publicat a:Biomolecules
Autors principals: Li, Qiao, Ning, Xiuzhe, Wang, Yuepeng, Zhu, Qing, Guo, Yan, Li, Hao, Zhou, Yusen, Kou, Zhihua
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6995627/
https://ncbi.nlm.nih.gov/pubmed/31842458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9120869
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