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Acyclic nucleoside thiophosphonates as potent inhibitors of HIV and HBV replication
9-[2-(Thiophosphonomethoxy)ethyl]adenine 3 and (R)-9-[2-(Thiophosphonomethoxy)propyl]adenine 4 were synthesized as the first thiophosphonate nucleosides bearing a sulfur atom at the α-position of the acyclic nucleoside phosphonates PMEA and PMPA. Thiophosphonates S-PMEA 3 and S-PMPA 4 were evaluated...
में बचाया:
| में प्रकाशित: | Eur J Med Chem |
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| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Elsevier Masson SAS.
2011
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7115536/ https://ncbi.nlm.nih.gov/pubmed/21803462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2011.06.034 |
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