SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling

SARS coronavirus (CoV) papain-like protease (PLpro) reportedly induced the production of TGF-β1 through p38 MAPK/STAT3-meidated Egr-1-dependent activation (Sci. Rep. 6, 25754). This study investigated the correlation of PLpro-induced TGF-β1 with the expression of Type I collagen in human lung epithe...

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Publicado no:Virus Res
Main Authors: Wang, Ching-Ying, Lu, Chien-Yi, Li, Shih-Wen, Lai, Chien-Chen, Hua, Chun-Hung, Huang, Su-Hua, Lin, Ying-Ju, Hour, Mann-Jen, Lin, Cheng-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114548/
https://ncbi.nlm.nih.gov/pubmed/28414040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2017.04.008
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