Characterization of the guanine-N7 methyltransferase activity of coronavirus nsp14 on nucleotide GTP

Most eukaryotic viruses that replicate in the cytoplasm, including coronaviruses, have evolved strategies to cap their RNAs. In our previous work, the nonstructural protein (nsp) 14 of severe acute respiratory syndrome coronavirus (SARS-CoV) was identified as a cap (guanine-N7)-methyltransferase (N7...

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Publicado no:Virus Res
Main Authors: Jin, Xu, Chen, Yu, Sun, Ying, Zeng, Cong, Wang, Yi, Tao, Jiali, Wu, Andong, Yu, Xiao, Zhang, Zhou, Tian, Jie, Guo, Deyin
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114466/
https://ncbi.nlm.nih.gov/pubmed/23702198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2013.05.001
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