Receptor tyrosine kinase inhibitors block proliferation of TGEV mainly through p38 mitogen-activated protein kinase pathways

Emerging coronaviruses (CoVs) primarily cause severe gastroenteric or respiratory diseases in humans and animals, and no approved therapeutics are currently available. Here, A9, a receptor tyrosine kinase inhibitor (RTKI) of the tyrphostin class, is identified as a robust inhibitor of transmissible...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Dong, Wanyu, Xie, Wenting, Liu, Yunbo, Sui, Baokun, Zhang, Hao, Liu, Liran, Tan, Yubei, Tong, Xiaohan, Fu, Zhen F., Yin, Ping, Fang, Liurong, Peng, Guiqing
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier B.V. 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114126/
https://ncbi.nlm.nih.gov/pubmed/31751591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2019.104651
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