Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase–induced inflammation

BACKGROUND: Immunity decreases with age, which leads to reactivation of varicella zoster virus (VZV). In human subjects age-associated immune changes are usually measured in blood leukocytes; however, this might not reflect alterations in tissue-specific immunity. OBJECTIVES: We used a VZV antigen c...

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Опубликовано в: :J Allergy Clin Immunol
Главные авторы: Vukmanovic-Stejic, Milica, Chambers, Emma S., Suárez-Fariñas, Mayte, Sandhu, Daisy, Fuentes-Duculan, Judilyn, Patel, Neil, Agius, Elaine, Lacy, Katie E., Turner, Carolin T., Larbi, Anis, Birault, Veronique, Noursadeghi, Mahdad, Mabbott, Neil A., Rustin, Malcolm H.A., Krueger, James G., Akbar, Arne N.
Формат: Artigo
Язык:Inglês
Опубликовано: Mosby 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6127037/
https://ncbi.nlm.nih.gov/pubmed/29155150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2017.10.032
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