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Regulation of Selective B Cell Autophagy by the Pro-oxidant Adaptor p66SHC
p66SHC is a pro-oxidant member of the SHC family of protein adaptors that acts as a negative regulator of cell survival. In lymphocytes p66SHC exploits both its adaptor and its reactive oxygen species (ROS)-elevating function to antagonize mitogenic and survival signaling and promote apoptosis. As a...
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| Publicado en: | Front Cell Dev Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2020
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7113388/ https://ncbi.nlm.nih.gov/pubmed/32274384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.00193 |
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