The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway

BACKGROUND: Although bone morphogenetic protein 6 (BMP6) signaling pathway has been implicated in many types of cancer, its role of tumorigenesis seems to be controversial and its ubiquitin-modifying mechanisms have not been fully addressed. Our study was designed to investigate how BMP6 signaling p...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Main Authors: Seo, Dongyeob, Jung, Su Myung, Park, Jin Seok, Lee, Jaewon, Ha, Jihoon, Kim, Minbeom, Park, Seok Hee
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2019
Assuntos:
Research paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7113187/
https://ncbi.nlm.nih.gov/pubmed/31685442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.10.039
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