Evolutionary aspects of lipoxygenases and genetic diversity of human leukotriene signaling

Leukotrienes are pro-inflammatory lipid mediators, which are biosynthesized via the lipoxygenase pathway of the arachidonic acid cascade. Lipoxygenases form a family of lipid peroxidizing enzymes and human lipoxygenase isoforms have been implicated in the pathogenesis of inflammatory, hyperprolifera...

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Bibliografiske detaljer
Udgivet i:Prog Lipid Res
Main Authors: Horn, Thomas, Adel, Susan, Schumann, Ralf, Sur, Saubashya, Kakularam, Kumar Reddy, Polamarasetty, Aparoy, Redanna, Pallu, Kuhn, Hartmut, Heydeck, Dagmar
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Ltd. 2015
Fag:
Review
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112624/
https://ncbi.nlm.nih.gov/pubmed/25435097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plipres.2014.11.001
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