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Lipoxygenase pathways in Homo neanderthalensis: functional comparison with Homo sapiens isoforms
Lipoxygenases (LOX) have been implicated in biosynthesis of pro- and anti-inflammatory mediators, and a previous report suggested compromised leukotriene signaling in H. neanderthalensis. To search for corresponding differences in leukotriene biosynthesis, we screened the Neandertal genome for LOX g...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3622333/ https://ncbi.nlm.nih.gov/pubmed/23475662 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M035626 |
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