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Protease inhibitors and their peptidomimetic derivatives as potential drugs

Precise spatial and temporal regulation of proteolytic activity is essential to human physiology. Modulation of protease activity with synthetic peptidomimetic inhibitors has proven to be clinically useful for treating human immunodeficiency virus (HIV) and hypertension and shows potential for medic...

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Detalhes bibliográficos
Publicado no:Pharmacol Ther
Main Authors: Fear, Georgie, Komarnytsky, Slavko, Raskin, Ilya
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112583/
https://ncbi.nlm.nih.gov/pubmed/17098288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2006.09.001
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