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Cosecretion of Protease Inhibitor Stabilizes Antibodies Produced by Plant Roots

A plant-based system for continuous production of monoclonal antibodies based on the secretion of immunoglobulin complexes from plant roots into a hydroponic medium (rhizosecretion) was engineered to produce high levels of single-chain and full-size immunoglobulins. Replacing the original signal pep...

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Main Authors: Komarnytsky, Slavko, Borisjuk, Nikolai, Yakoby, Nir, Garvey, Alison, Raskin, Ilya
Format: Artigo
Jezik:Inglês
Izdano: American Society of Plant Biologists 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1533931/
https://ncbi.nlm.nih.gov/pubmed/16896231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1104/pp.105.074419
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