Development of robust in vitro RNA-dependent RNA polymerase assay as a possible platform for antiviral drug testing against dengue

NS5 is the largest and most conserved protein among the four dengue virus (DENV) serotypes. It has been the target of interest for antiviral drug development due to its major role in replication. NS5 consists of two domains, the N-terminal methyltransferase domain and C-terminal catalytic RNA-depend...

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Detaylı Bibliyografya
Yayımlandı:Enzyme Microb Technol
Asıl Yazarlar: Amraiz, Deeba, Zaidi, Najam-us-Sahar Sadaf, Fatima, Munazza
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier Inc. 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112394/
https://ncbi.nlm.nih.gov/pubmed/27542741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.enzmictec.2016.06.010
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