Structural and functional conservation of cis-acting RNA elements in coronavirus 5'-terminal genome regions

Structure predictions suggest a partial conservation of RNA structure elements in coronavirus terminal genome regions. Here, we determined the structures of stem-loops (SL) 1 and 2 of two alphacoronaviruses, human coronavirus (HCoV) 229E and NL63, by RNA structure probing and studied the functional...

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Publicado no:Virology
Main Authors: Madhugiri, Ramakanth, Karl, Nadja, Petersen, Daniel, Lamkiewicz, Kevin, Fricke, Markus, Wend, Ulrike, Scheuer, Robina, Marz, Manja, Ziebuhr, John
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112051/
https://ncbi.nlm.nih.gov/pubmed/29223446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.11.025
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