Direct RNA nanopore sequencing of full-length coronavirus genomes provides novel insights into structural variants and enables modification analysis

Sequence analyses of RNA virus genomes remain challenging owing to the exceptional genetic plasticity of these viruses. Because of high mutation and recombination rates, genome replication by viral RNA-dependent RNA polymerases leads to populations of closely related viruses, so-called “quasispecies...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Genome Res
Auteurs principaux: Viehweger, Adrian, Krautwurst, Sebastian, Lamkiewicz, Kevin, Madhugiri, Ramakanth, Ziebuhr, John, Hölzer, Martin, Marz, Manja
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2019
Sujets:
Method
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724671/
https://ncbi.nlm.nih.gov/pubmed/31439691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.247064.118
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires