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S gene and 5a accessory gene are responsible for the attenuation of virulent infectious bronchitis coronavirus

To explore the critical genes associated with infectious bronchitis virus (IBV) virulence, we compared the genome sequences of virulent YN strain and its attenuated strain aYN. Accumulation of mutations in the S gene and the accessory gene 5a were observed, suggesting a potential role in the loss of...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Virology
Asıl Yazarlar: Zhao, Ye, Cheng, Jinlong, Yan, Shihong, Jia, Wenfeng, Zhang, Keran, Zhang, Guozhong
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Authors. Published by Elsevier Inc. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112010/
https://ncbi.nlm.nih.gov/pubmed/31078931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2019.04.014
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