The S2 Subunit of QX-type Infectious Bronchitis Coronavirus Spike Protein Is an Essential Determinant of Neurotropism

Some coronaviruses (CoVs) have an extra furin cleavage site (RRKR/S, furin-S2′ site) upstream of the fusion peptide in the spike protein, which plays roles in virion adsorption and fusion. Mutation of the S2′ site of QX genotype (QX-type) infectious bronchitis virus (IBV) spike protein (S) in a reco...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Cheng, Jinlong, Zhao, Ye, Xu, Gang, Zhang, Keran, Jia, Wenfeng, Sun, Yali, Zhao, Jing, Xue, Jia, Hu, Yanxin, Zhang, Guozhong
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6832359/
https://ncbi.nlm.nih.gov/pubmed/31652591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v11100972
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