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S gene and 5a accessory gene are responsible for the attenuation of virulent infectious bronchitis coronavirus
To explore the critical genes associated with infectious bronchitis virus (IBV) virulence, we compared the genome sequences of virulent YN strain and its attenuated strain aYN. Accumulation of mutations in the S gene and the accessory gene 5a were observed, suggesting a potential role in the loss of...
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| Publicado no: | Virology |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Authors. Published by Elsevier Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7112010/ https://ncbi.nlm.nih.gov/pubmed/31078931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2019.04.014 |
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