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Replication of murine coronavirus requires multiple cysteines in the endodomain of spike protein

A conserved cysteine-rich motif located between the transmembrane domain and the endodomain is essential for membrane fusion and assembly of coronavirus spike (S) protein. Here, we proved that three cysteines within the motif, but not dependent on position, are minimally required for the survival of...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Yang, Jinhua, Lv, Jun, Wang, Yuyan, Gao, Shuang, Yao, Qianqian, Qu, Di, Ye, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111998/
https://ncbi.nlm.nih.gov/pubmed/22424735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.02.015
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