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Replication of murine coronavirus requires multiple cysteines in the endodomain of spike protein

A conserved cysteine-rich motif located between the transmembrane domain and the endodomain is essential for membrane fusion and assembly of coronavirus spike (S) protein. Here, we proved that three cysteines within the motif, but not dependent on position, are minimally required for the survival of...

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Библиографические подробности
Опубликовано в: :Virology
Главные авторы: Yang, Jinhua, Lv, Jun, Wang, Yuyan, Gao, Shuang, Yao, Qianqian, Qu, Di, Ye, Rong
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier Inc. 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111998/
https://ncbi.nlm.nih.gov/pubmed/22424735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2012.02.015
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