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Partial deletion in the spike endodomain of mouse hepatitis virus decreases the cytopathic effect but maintains foreign protein expression in infected cells

Mouse hepatitis virus (MHV) produces a series of subgenomic RNAs for viral protein expression. As a prototype coronavirus, MHV has been explored extensively and is often used to express foreign proteins. Previously, a 13-residue deletion in the MHV spike (S) protein endodomain was found to reduce sy...

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Detalhes bibliográficos
Publicado no:J Virol Methods
Main Authors: Yang, Jinhua, Sun, Zhiping, Wang, Yuyan, Lv, Jun, Qu, Di, Ye, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7112841/
https://ncbi.nlm.nih.gov/pubmed/21192978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2010.12.018
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