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Two-amino acids change in the nsp4 of SARS coronavirus abolishes viral replication

Infection with coronavirus rearranges the host cell membrane to assemble a replication/transcription complex in which replication of the viral genome and transcription of viral mRNA occur. Although coexistence of nsp3 and nsp4 is known to cause membrane rearrangement, the mechanisms underlying the i...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Sakai, Yusuke, Kawachi, Kengo, Terada, Yutaka, Omori, Hiroko, Matsuura, Yoshiharu, Kamitani, Wataru
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111695/
https://ncbi.nlm.nih.gov/pubmed/28738245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.07.019
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