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Two-amino acids change in the nsp4 of SARS coronavirus abolishes viral replication

Infection with coronavirus rearranges the host cell membrane to assemble a replication/transcription complex in which replication of the viral genome and transcription of viral mRNA occur. Although coexistence of nsp3 and nsp4 is known to cause membrane rearrangement, the mechanisms underlying the i...

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Dades bibliogràfiques
Publicat a:Virology
Autors principals: Sakai, Yusuke, Kawachi, Kengo, Terada, Yutaka, Omori, Hiroko, Matsuura, Yoshiharu, Kamitani, Wataru
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111695/
https://ncbi.nlm.nih.gov/pubmed/28738245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.07.019
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