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Cell-Nonautonomous Regulation of Proteostasis in Aging and Disease

The functional health of the proteome is determined by properties of the proteostasis network (PN) that regulates protein synthesis, folding, macromolecular assembly, translocation, and degradation. In eukaryotes, the PN also integrates protein biogenesis across compartments within the cell and betw...

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Bibliographic Details
Published in:Cold Spring Harb Perspect Biol
Main Author: Morimoto, Richard I.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2020
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111247/
https://ncbi.nlm.nih.gov/pubmed/30962274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a034074
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