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Embryo integrity regulates maternal proteostasis and stress resilience

The proteostasis network is regulated by transcellular communication to promote health and fitness in metazoans. In Caenorhabditis elegans, signals from the germline initiate the decline of proteostasis and repression of cell stress responses at reproductive maturity, indicating that commitment to r...

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Pubblicato in:Genes Dev
Autori principali: Sala, Ambre J., Bott, Laura C., Brielmann, Renee M., Morimoto, Richard I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197353/
https://ncbi.nlm.nih.gov/pubmed/32217667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.335422.119
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