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Alignment independent 3D-QSAR studies and molecular dynamics simulations for the identification of potent and selective S1P(1) receptor agonists
Sphingosine 1-phosphate type 1 (S1P(1)) receptors are expressed on lymphocytes and regulate immune cells trafficking. Sphingosine 1-phosphate and its analogues cause internalization and degradation of S1P(1) receptors, preventing the auto reactivity of immune cells in the target tissues. It has been...
Gorde:
| Argitaratua izan da: | J Mol Graph Model |
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| Egile Nagusiak: | , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Elsevier Inc.
2020
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7110456/ https://ncbi.nlm.nih.gov/pubmed/31589999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2019.107459 |
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