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Prediction of the Human EP1 Receptor Binding Site by Homology Modeling and Molecular Dynamics Simulation
The prostanoid receptor EP1 is a G-protein-coupled receptor (GPCR) known to be involved in a variety of pathological disorders such as pain, fever and inflammation. These receptors are important drug targets, but design of subtype specific agonists and antagonists has been partially hampered by the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Österreichische Apotheker-Verlagsgesellschaft
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3221501/ https://ncbi.nlm.nih.gov/pubmed/22145106 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3797/scipharm.1106-24 |
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