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RAD51 discrimination between single‐ and double‐strand DNA: a matter of flexibility and enthalpy
In selecting ssDNA over dsDNA, the RAD51 DNA strand exchange protein has to overcome the entropy associated with straightening of single‐strand DNA upon nucleoprotein filament formation. New work in The EMBO Journal (Paoletti et al, 2020), combined biophysical analysis of the RAD51–ssDNA interaction...
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| Pubblicato in: | EMBO J |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
John Wiley and Sons Inc.
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7110141/ https://ncbi.nlm.nih.gov/pubmed/32090346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020104547 |
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