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Histone-induced thrombotic thrombocytopenic purpura in adamts13(−/−) zebrafish depends on von Willebrand factor
Thrombotic thrombocytopenic purpura (TTP) is caused by severe deficiency of ADAMTS13 (A13), a plasma metalloprotease that cleaves endothelium-derived von Willebrand factor (VWF). However, severe A13 deficiency alone is often not sufficient to cause an acute TTP; additional factors may be required to...
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| Publié dans: | Haematologica |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Ferrata Storti Foundation
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7109750/ https://ncbi.nlm.nih.gov/pubmed/31753928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.237396 |
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