A carregar...
The role of neuraminidase 1 and 2 in glycoprotein Ibα-mediated integrin αIIbβ3 activation
Upon vascular injury, platelets adhere to von Willebrand Factor (VWF) via glycoprotein Ibα (GPIbα). GPIbα contains many glycans, capped by sialic acid. Sialic acid cleavage (desialylation) triggers clearance of platelets. Neuraminidases (NEU) are responsible for desialylation and so far, NEU1-4 have...
Na minha lista:
| Publicado no: | Haematologica |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Ferrata Storti Foundation
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7109719/ https://ncbi.nlm.nih.gov/pubmed/31273092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2019.215830 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|