Pregnancy-Specific Glycoproteins Bind Integrin αIIbβ3 and Inhibit the Platelet—Fibrinogen Interaction

Pregnancy-specific glycoproteins (PSGs) are immunoglobulin superfamily members encoded by multigene families in rodents and primates. In human pregnancy, PSGs are secreted by the syncytiotrophoblast, a fetal tissue, and reach a concentration of up to 400 ug/ml in the maternal bloodstream at term. Hu...

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Detalhes bibliográficos
Main Authors: Shanley, Daniel K., Kiely, Patrick A., Golla, Kalyan, Allen, Seamus, Martin, Kenneth, O’Riordan, Ronan T., Ball, Melanie, Aplin, John D., Singer, Bernhard B., Caplice, Noel, Moran, Niamh, Moore, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3585349/
https://ncbi.nlm.nih.gov/pubmed/23469002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0057491
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